Table 5 Baseline functional, quality of life (N%) or mean (SD)/median (IQR)
PHOENIx participants (n = 128) | |
|---|---|
Frailty criteria h | |
Weight loss | 67 (65%) |
Exhaustion | 92 (77.3%) |
Low activity | 88 (69.8%) |
Slowness | 75 (66.4%) |
Weakness | 28 (25.2%) |
Positive for frailty phenotype | 50 (70.4%) |
Pre-frail | 20 (28.2%) |
Quality of life (EQ5D5L)b | |
Mobility | 3 (1–4) |
(1 = no problem; 2 = slight; 3 = moderate; 4 = severe; 5 = unable to mobilise) | |
Self-care | 2 (1–3) |
(1 = no problem; 2 = slight; 3 = moderate; 4 = severe; 5 = unable to self-care) | |
Usual activities | 3 (1–4) |
(1 = no problem; 2 = slight; 3 = moderate; 4 = severe; 5 = unable to do usual activities) | |
Pain/discomfort | 3 (2–4) |
(1 = no problem; 2 = slight; 3 = moderate; 4 = severe; 5 = extreme pain/discomfort) | |
Anxiety/depression | 4 (3–5) |
(1 = no problem; 2 = slight; 3 = moderate; 4 = severe; 5 = extreme) | |
Overall health number—Visual Analogue Scale (VAS)c | 34.4 (23.9) |
(0 = worst health imaginable; 100 = best health imaginable) | |
Index Score—crosswalk method to UK Value Set | 0.2 (0.3) |
(− 0.5 = lowest score on all five domains; 1 = highest score on all five domains) | |
Mealsc1 | |
Breakfast, lunch and dinner | 35 (28.5%) |
One meal only per day | 34 (27.6%) |
Two meals only per day | 34 (27.6%) |
No daily meals | 20 (16.3%) |
Modified Medical Research Council breathlessness scaled1 | 2 (1–3)d |
Oxygen saturation (%)g | 96.4% (2.3%) |
Peak expiratory flow rate (% predicted, l/min)i | 70.6 (21.5) |
Systolic blood pressure (mmHg)e | 115.8 (18.5) |
Heart rate (beats per minute)f | 78.3 (14.0) |
Sodium (133–146 mmol/l)k | 103 (95.4%) |
Mean (SD) | 138.5 (3.2) |
Potassium (3.5–5.3 mmol/l)l | 104 (95.4) |
Mean (SD) | 4.2 (0.5) |
Creatinine (40–130umol/l)m | 108 (99.1%) |
Mean (SD) | 68.4 (15.1) |
Estimated GFR (% > 60 ml/min)m | 106 (97.2%) |
Alanine aminotransferase (% < 50 U/L)n | 86 (80.4%) |
Mean (SD) | 30.9 (28.6) |
Asparate aminotransferase (% < 40 U/L)0 | 80 (75.5%) |
Mean (SD) | 40.2 (40.7) |
Alkaline phosphatase (< 130 U/L)0 | 89 (84.0%) |
Mean (SD) | 103.9 (56.1) |
Albumin (> 35 g/l)m | 63 (57.8%) |
Mean (SD) | 36.5 (5.6) |
Calcium (adj 2.2–2.6)t | 77 (89.5%) |
Mean (SD) | 2.3 (0.1) |
Magnesium (> 0.7 mmol/l)p | 52 (81.2%) |
Mean (SD) | 0.8 (0.2) |
C-reactive protein (< 10 mg/l)q | 53 (51.5%) |
Mean (SD) | 19.4 (28.7) |
B12 (200–883 ng/l)r | 20 (90.9%) |
Mean (SD) | 508.3 (217.4) |
Folate (serum: 3.1–20.0 ng/ml)s | 11 (47.6%) |
Mean (SD) | 4.3 (2.4) |
Red cell count (4.5–6.5)u | 33 (31.1%) |
Mean (SD) | 2.3 (0.1) |
Platelets (150–410)u | 96 (90.6%) |
Mean (SD) | 258 (85.6) |