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Table 1 Summary of study and patient characteristics

From: Controlled-release hydromorphone and risk of infection in adults: a systematic review

Characteristics

Number (%)

Study characteristics (n = 7)

 

Year of publication

 

2020

4 (80%)

2021

1 (20%)

Geographical region

 

Canada

5 (100%)

Study design

 

Cohort

4 (80%)

Case control

1 (20%)

Study duration

 

 ≤ 1 year

2 (40%)

 ≤ 5 years

2 (40%)

 > 5 years

1 (20%)

Setting

 

Multi-site

4 (80%)

Single site

1 (20%)

Patient characteristics

 

Total # patients

4,208

Mean number of patients (range)

4,015 (26–3,790)

Mean % female patients (range)

48.425 (42.5–54)

Age (mean/median)

 

 ≤ 40 years

1 (20%)

 > 40 years

1 (20%)

Not reported

3 (60%)

Studies reporting on outcomesa

 

Infective endocarditis

1

HCV

4

HIV

2

Comorbiditiesa

 

Alcohol use disorder

3

Stimulant use disorder

1

Psychiatric diagnosis

3

HCV

3

Untreated HCV

1

HIV

3

Hepatitis B

2

Chronic liver disease

1

Coronary artery disease

1

Congestive heart failure

1

Self-harm

2

Psychiatric medication at enrolment

1

HAART

1

Injection related complication

1

Not reported

2

  1. Abbreviations: HIV, Human immunodeficiency virus; HCV, Hepatitis C virus; HAART, highly active antiretroviral therapy
  2. aMultiple categories reported per study