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Table 2 Product choice by factors influencing choice and willingness to administer

From: Bystander preference for naloxone products: a field experiment

 

Total

Higher-dose nasal spray (HS)

Lower-dose nasal spray (LS)

Intramuscular injection (II)

HS versus LSa (p-value)

HS versus IIb (p-value)

LS versus IIc (p-value)

(N = 509)

(N = 226)

(N = 130)

(N = 153)

Please rate how each of the following factors influenced your choice to take [self_choice] home with you today

 Dose of naloxone in the product

    

 < 0.001

 < 0.001

1

  Median [Q1, Q3]

8.00 [5.00, 10.0]

9.00 [6.00, 10.0]

6.00 [5.00, 9.00]

7.00 [5.00, 9.00]

  Missing

45 (8.8%)

16 (7.1%)

13 (10.0%)

16 (10.5%)

 Ease of use

    

d

  Median [Q1, Q3]

9.00 [7.00, 10.0]

9.00 [7.00, 10.0]

9.00 [7.00, 10.0]

9.00 [6.00, 10.0]

  Missing

34 (6.7%)

18 (8.0%)

7 (5.4%)

9 (5.9%)

 Familiarity with the product (i.e., I have heard of this product before)

    

< 0.001

0.092

 < 0.001

  Median [Q1, Q3]

5.00 [5.00, 9.00]

5.00 [2.00, 7.25]

9.00 [5.00, 10.0]

5.00 [5.00, 9.00]

  Missing

52 (10.2%)

26 (11.5%)

9 (6.9%)

17 (11.1%)

 Fear of needles

    

0.063

0.001

 < 0.001

  Median [Q1, Q3]

2.00 [0, 6.00]

3.00 [0, 6.00]

5.00 [0, 9.00]

0 [0, 4.25]

  Missing

43 (8.4%)

20 (8.8%)

10 (7.7%)

13 (8.5%)

 Concern for injuring myself with the used needle

    

0.201

0.033

 < 0.001

  Median [Q1, Q3]

2.00 [0, 5.00]

3.00 [0, 5.00]

5.00 [0, 9.00]

1.00 [0, 5.00]

  Missing

47 (9.2%)

22 (9.7%)

13 (10.0%)

12 (7.8%)

 Potential side effects

    

0.002

1

0.038

  Median [Q1, Q3]

3.00 [0, 5.00]

2.00 [0, 5.00]

5.00 [0.250, 5.75]

2.00 [0, 5.00]

  Missing

64 (12.6%)

29 (12.8%)

16 (12.3%)

19 (12.4%)

How willing are you to administer each of them to reverse an opioid overdose?

 Higher-Dose Nasal Spray

    

0.125

0.03

1

  Median [Q1, Q3]

10.0 [8.00, 10.0]

10.0 [9.00, 10.0]

10.0 [8.00, 10.0]

10.0 [7.00, 10.0]

  Missing

39 (7.7%)

15 (6.6%)

12 (9.2%)

12 (7.8%)

 Lower-Dose Nasal Spray

    

  Median [Q1, Q3]

10.0 [8.00, 10.0]

10.0 [8.00, 10.0]

10.0 [9.00, 10.0]

10.0 [7.50, 10.0]

  Missing

38 (7.5%)

20 (8.8%)

8 (6.2%)

10 (6.5%)

 Intramuscular Injection

    

1

 < 0.001

 < 0.001

  Median [Q1, Q3]

9.00 [5.00, 10.0]

8.00 [5.00, 10.0]

8.00 [5.00, 10.0]

10.0 [9.00, 10.0]

  Missing

51 (10.0%)

27 (11.9%)

19 (14.6%)

5 (3.3%)

  1. aThe pairwise comparison between higher-dose nasal spray and lower-dose nasal spray (based on the naloxone products preferred taken home)
  2. bThe pairwise comparison between higher-dose nasal spray and intramuscular injection (based on the naloxone products preferred taken home)
  3. cThe pairwise comparison between lower-dose nasal spray and intramuscular injection (based on the naloxone products preferred taken home)
  4. dThe overall test among three groups were insignificant (p > 0.05); thus no subsequent pairwise comparison was conducted