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Table 7 Mediation of the effect of social determinants of health on substance-use through mental health

From: The associations between social determinants of health, mental health, substance-use and recidivism: a ten-year retrospective cohort analysis of women who completed the connections programme in Australia

Relationship a

Total effect

Direct effect

(SE)

p-value

Indirect effect (SE)

Confidence intervals b

Conclusion

Lower bound

Upper bound

Housing—> Mental health—> Substance-use

 − 0.21

0.12 (0.26)

0.64

 − 0.33 (0.10)

0.16

0.57

Full mediation

Employment—> Mental health—> Substance-use

 − 0.22

 − 0.32 (0.46)

0.48

0.10 (0.13)

 − 0.13

0.36

No mediation

Financial—> Mental health—> Substance-use

0.51

0.37 (0.24)

0.12

0.15 (0.07)

0.03

0.30

Full mediation

Education—> Mental health—> Substance-use

0.71

 − 0.19 (0.50)

0.70

0.90 (0.14)

 − 0.17

0.38

No mediation

Domestic violence—> Mental health—> Substance-use

1.81

1.24 (0.63)

0.05

0.57 (0.23)

0.21

1.10

Partial mediation

Child-custody—> Mental health—> Substance-use

0.54

0.36 (0.30)

0.24

0.18 (0.10)

0.01

0.39

Full mediation

Social support—> Mental health—> Substance-use

0.84

0.48 (0.27)

0.07

0.36 (0.11)

0.18

0.59

Full mediation

  1. Bold: Significance was determined if the entire interval lies on one side of the null hypothesis value (i.e., 0). This indicates statistical significance at the chosen significance level (i.e., 95% confidence level)
  2. SE = standard error
  3. a Adjusted for admission year and age
  4. b10,000 bootstrap samples were used for percentile confidence intervals