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Table 1 Rapid low dose (4-day) and standard low dose (7-day) initiation protocol dosing schedules

From: Withdrawal during outpatient low dose buprenorphine initiation in people who use fentanyl: a retrospective cohort study

Day of protocol

Rapid (4-day) protocol

Standard (7-day) protocol

1

0.5 mg every 6 h

0.5 mg once

2

1 mg every 6 h

0.5 mg in the morning and evening

3

2 mg every 6 h

0.5 mg in the morning, then 1 mg in the afternoon and evening

4

12 mg in the morning, then follow up with provider

2 mg in the morning and evening

5

 

3 mg in the morning and evening

6

 

4 mg in the morning and evening

7

 

12 mg in the morning, then follow up with provider