A reduced exposure heated tobacco product was introduced then abruptly taken off United States shelves: results from a tobacco harm reduction natural experiment

Table 4 General linear model estimates predicting CPW after HTP removal

Predictor	Estimate	95% CI	t-value	Pr > t
Intercept	102.78	88.76, 116.79	14.41	< 0.0001
Mean centered CPW before HTP initiation	0.677	0.603, 0.750	18.09	< 0.0001
HTP current use versus non-use	− 18.802	− 33.960, − 3.645	− 2.44	0.0152
ENDS current use versus non-use	− 32.908	− 46.214, − 19.603	− 4.86	< 0.0001
Other non-combustible current use versus non-use	− 0.565	− 25.023, 23.893	− 0.05	0.9638
Male versus female	5.607	− 7.772, 18.987	0.82	0.4106
21–34 years old versus 35–49 years old	− 16.747	− 34.954, 1.460	− 1.81	0.0713
50–64 years old versus 35–49 years old	− 14.357	− 29.720, 1.005	− 1.84	0.0669
65 + years old versus 35–49 years old	− 16.732	− 45.438, 11.974	− 1.15	0.2526
Black/AA versus White	− 13.146	− 38.264, 11.971	− 1.03	0.3042
Asian, Indian, PI versus White	0.639	− 24.538, 25.816	0.05	0.9602
Multiracial, Hispanic, Other versus White	− 14.339	− 38.131, 9.453	− 1.18	0.2369

Italicized groups refer to the reference category. The model estimates cigarettes per week after HTP removal while accounting for cigarettes per week before the HTP initiation, other tobacco use behaviors, gender, age, and race. Other non-combustible tobacco use included smokeless tobacco pouches and nicotine pouches. “Non-use” as a reference category refers to not using that particular tobacco product

ISSN: 1477-7517