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Table 1 Example of flexibility in IOT prescription

From: Methodology for the Randomised Injecting Opioid Treatment Trial (RIOTT): evaluating injectable methadone and injectable heroin treatment versus optimised oral methadone treatment in the UK

 

Drug & route

Dose & time

Regime A

Diamorphine (IV or IM)

Diamorphine (IV or IM)

Methadone (oral)

200 mg morning

200 mg afternoon

30 mg evening

Regime B

Diamorphine (IV or IM)

Methadone (oral)

200 mg (daily)

100 mg (daily)

Regime C

Methadone (oral)

160 mg