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Table 2 Methadone and ART

From: Impact of a methadone maintenance therapy pilot in Vietnam and its role in a scaled-up response

  Follow-up periods p value
  0–3 months 4–6 months 7–9 months 10–12 months 13–18 months 19–24 months
  (n = 930) (n = 900) (n = 871) (n = 852) (n = 802) (n = 751)
Mean methadone doses at study visits, in ml (SE)
 Hai Phong 9.6 (0.2) 9.9 (0.2) 9.5 (0.2) 9.5 (0.3) 9.4 (0.3) 9.6 (0.3) 0.248a
 HCMC 10.6 (0.2) 11.0 (0.3) 11.2 (0.3) 11.4 (0.3) 11.5 (0.4) 11.6 (0.4) 0.000a
 Total 10.1 (0.1) 10.4 (0.2) 10.4 (0.2) 10.4 (0.2) 10.4 (0.2) 10.6 (0.3) 0.000a
Missed methadone dose for 1–2 days, in %
 Hai Phong 19.5 23.6 30.7 41.1 48.4 47.7 0.000a
 HCMC 17.3 22.0 26.5 28.1 33.8 34.7 0.000a
 Total 18.4 22.8 28.6 34.6 41.3 41.4 0.000a
Missed methadone doses for continuous 3–4 days, in %
 Hai Phong 1.3 0.9 1.8 1.9 2.2 3.4 0.009a
 HCMC 0.6 0.9 1.4 0.7 1.0 4.1 0.000a
 Total 1.0 0.9 1.6 1.2 1.6 3.7 0.000a
Missed methadone doses for a continuous 5 days or more, in %
 Hai Phong 0.9 1.1 1.1 1.2 2.2 2.3 0.025a
 HCMC 1.3 0.9 1.4 0.9 3.3 4.1 0.000a
 Total 1.1 1.0 1.3 1.1 2.7 3.2 0.000a
ARV treatment, in %
 Hai Phong 14.2 12.9 15.1 14.0 16.3 16.0 0.202a
 HCMC 39.8 50.8 35.9 38.7 41.2 43.3 0.846a
 Total 27.2 31.9 25.5 26.3 28.4 29.2 0.827a
  1. aTest for trend