Fig. 3
From: The effects of heat and freeze-thaw cycling on naloxone stability
Parabens are not affected by exposure to freeze-thaw cycles. a The concentrations of both total parabens and the paraben degradation byproduct remain unchanged (evaluated as AUC) after 28 days of exposure to freeze-thaw cycles. The left axis corresponds to the AUC for the parabens whereas the right axis corresponds to the AUC for the paraben degradation product. b The percent of paraben degradation product relative to total parabens as a function of time. The degraded paraben byproduct concentration remained the same after 28 days of exposure to freeze-thaw cycles