Toxicity classification of e-cigarette flavouring compounds based on European Union regulation: analysis of findings from a recent study

Table 3 Toxicity classification of a mixture containing all flavouring chemicals at the maximum concentrations reported by Vardavas et al.

Classification hazard	ATEmix or total concentration (%) of all compounds with the same hazard classification	ATEmix limit or minimum concentration for classification of toxicity	% difference¹
Η302 Category 4	4726	≤ 2000	− 57.7%
Η304 Category 1	0.0001	10	> − 99.9%
Η315 Category 2	1.7824	10	− 82.2%
Η317 Category 1	0.3451	1	− 65.5%
Η319 Category 2	4.289	10	− 57.1%
Η334 Category 1	2.5187	1	151.9%
Η335 Category 3	3.5269	10	− 64.7%
Η400 Category 1	0.0077	25	> − 99.9%
Η410 Category 1	0.0001	25	> − 99.9%
Η411 Category 2	0.0896	25	− 99.6%
Η412 Category 3	0.9255	25	− 96.3%

¹Percent difference between the maximum concentration reported by Vardavas et al. and the concentration needed to be classified as toxic
Italics represents the compound and hazard exceeding the limits for toxicity classification

ISSN: 1477-7517