Participants using CCM | Participants using CCM and heroin | All participants |
---|---|---|
 |  | CWE was used to eliminate non-opioid analgesics (paracetamol and ibuprofen) to reduce the risk of paracetamol overdose. |
The many steps involved (including sourcing OTC CCM from multiple pharmacies) made CWE less attractive. | Â | Â |
 | Cravings outweighed concerns about the ineffectiveness of CWE and triggered utilisation. |  |
 |  | Online information influenced use of CWE (facilitated tampering of psychoactive medicines but also reduced the risk of harm associated with paracetamol overdose). |
 | Concerns of injecting tablet fillers in solutions containing crushed tablets facilitated use of CWE. |  |
 | When stronger codeine (prescription-only CCM) were not accessible, participants treated OTC codeine-containing tablets with CWE. |  |
 | Reduced supply of heroin would lead participants to source other types of opioids including utilisation of CWE. |  |