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Table 1 Patient COWS by individual category [6]

From: Buprenorphine therapy in the setting of induced opioid withdrawal from oral naltrexone: a case report

Time 1000 1100 1230 1315 1445
Resting pulse rate 0 1 0 0 1
Sweating 2 2 2 1 1
Restlessness 3 3 3 0 0
Pupil size 2 2 1 1 1
Bone or joint aches 2 2 1 1 1
Runny nose or tearing 2 2 0 0 0
GI upset 5 3 3 0 0
Tremor 2 1 0 0 0
Yawning 1 1 0 0 1
Anxiety or irritability 2 4 2 0 1
Piloerection (“gooseflesh skin”) 5 5 3 0 0
Score 26 26 15 3 6