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Table 2 Eligible article characteristics (n = 22)

From: Facilitators and barriers to the regulation of medical cannabis: a scoping review of the peer-reviewed literature

First author and year

Article title

Country of first author

Countries discussed

Study design

Study aim

Ablin et al. 2016 [27]

Medical use of cannabis products: Lessons to be learned from Israel and Canada

Israel

Canada, Germany and Israel

Policy analysis

To examine the different aspects of MC and regulatory frameworks surrounding MC, as well as, how these regulations can be applied in Germany

Bradford et al. 2017 [3]

Factors driving the diffusion of medical marijuana legalisation in the United States

United States

United States

Policy analysis

A review of how the adoption of medical marijuana laws spread across the US, along with a review of the factors affecting the policy diffusion

Campbell et al. 2015 [26]

The medical marijuana catch-22: How the federal monopoly on marijuana research unfairly handicaps the rescheduling movement

United States

United States

Policy analysis

To analyze MC policies in the US and the categorization of cannabis as a Schedule I drug

Choo et al. 2017 [18]

Clearing the haze: The complexities and challenges of research on state marijuana laws

United States

United States

Literature review

To provide an overview of marijuana laws in the US, in addition to a review of the status of policy research in the US while highlighting issues and the considerations brought to attention during the policy development process; to examine areas in the policy development process that require further research and development

Cohen et al. 2010 [28]

Medical marijuana 2010: It's time to fix the regulatory vacuum

United States

United States

Literature review

To conduct a literature review on the history of MC laws in the US, as well as, to provide an overview of the current MC laws

Davenport et al. 2016 [30]

The Dangerous Drugs Act Amendment in Jamaica: Reviewing goals, implementation, and challenges

United States

Jamaica and the United States

Policy analysis

To analyze how the Dangerous Drug Amendment Act influences populations across Jamaica, achieves its stated goals, and the various challenges faced by the implementation process of the regulatory framework

Flexon et al. 2019 [19]

The effect of cannabis laws on opioid use

United States

United States

Policy analysis

To investigate the effect of medicinal marijuana laws on opioid users, and whether individuals with chronic pain are opting to use medicinal marijuana instead of opioids due to the law changes

Grbic et al. 2017 [20]

Observations of the role of science in the United States medical cannabis state policies: Lessons learnt

United States

United States

Policy analysis

To identify the main challenges to the development of MC laws in the US

Hammer et al. 2015 [21]

Patients, police, and care providers: The cultural dimension of medical marijuana implementation

United States

United States

Policy analysis

To test the social construction theory and utilize the Institutional Analysis and Design framework to determine the role political culture has on MC regulation and implementation

Heddleston et al. 2013 [15]

A tale of three cities: Medical marijuana, activism, and local regulation in California

United States

United States

Case study

To examine the MC policies and regulations in three US cities, including Los Angeles, San Diego, and San Francisco using three different models

Kim et al. 2018 [13]

Policy innovation and diffusion through policy typologies: Examining the predictors of medical marijuana legalization in states

United States

United States

Policy analysis

To evaluate factors that contribute to the diffusion of medical marijuana laws; the type of policies that determines whether a medical marijuana policy is adopted or not; and, how the adoption of medical marijuana laws affects the legalization of medical marijuana in the state

Lamonica et al. 2016 [9]

Gaps in medical marijuana policy implementation: Real-time perspectives from marijuana dispensary entrepreneurs, health care professionals and medical marijuana patients

United States

United States

Policy analysis

To review the recent changes in marijuana policy in Massachusetts and examine the challenges for its implementation

Lucas et al. 2008 [1]

Regulating compassion: An overview of Canada's federal medical cannabis policy and practice

Canada

Canada

Policy analysis

To examine the origin and evolution of Health Canada's MMAD, Canadian Institute of Health Research Medical Marijuana Research Program and Prairie plant system, and the Canadian federal contract

Lucas et al. 2012 [22]

It can't hurt to ask; A patient-centered quality of service assessment of Health Canada's medical cannabis policy and program

Canada

Canada

Survey and Interviews

To gain knowledge about the needs of patients who have been federally authorized for MC, as well as, the challenges and experiences associated with Health Canada's Marihuana Medical Access Division

Miyaji et al. 2016 [23]

Tackling the pharmaceutical frontier: Regulation of cannabinoid-based medicines in postwar Japan

Japan

Japan

Literature review

To explore the history of the development of MC and discuss the control of cannabis and the status of research on MC in Japan

Pacula et al. 2002 [31]

State medical marijuana laws: Understanding the laws and their limitations

United States

United States

Policy analysis

To present original legal research on current MC laws and regulations in all 50 states in the US

Pacula et al. 2014 [14]

Words can be deceiving: A review of variation among legally effective medical marijuana laws in the United States

United States

United States

Literature review

To determine the characteristics of MMLs that have been established in 1990; specifically, the study examined factors associated with consumers/patients, the influence of the MMLs on access, and an overall examination of the variation amongst the laws

Pardo et al. 2014 [24]

Cannabis policy reforms in the Americas: A comparative analysis of Colorado, Washington, and Uruguay

United States

United States and Uruguay

Policy analysis

To explore policies on cannabis legalization in Uruguay and Colorado and Washington, and to provide policymakers with data that allowed for a deeper understanding of the policies and challenges associated with cannabis reform

Smith et al. 2013 [17]

Medical marijuana regulation in Michigan: Problems of legitimacy

United States

United States

Case study

To analyze the Michigan Medical Marijuana Act (MMMA) and examine the social issues that arose during the development process of the regulation

Taylor et al. 2016 [25]

Evidence-based policy? The re-medicalization of cannabis and the role of expert committees in the UK, 1972–1982

United Kingdom

United Kingdom

Case study

To examine the role of UK-based expert groups during the implementation process of MC policies from 1972 to 1982

Tilburg et al. 2019 [16]

Emerging public health law and policy issues concerning state medical cannabis programs

United States

United States

Policy analysis

To examine how restrictions on cannabis, imposed by federal laws, impede the development of regulatory frameworks for cannabis ultimately affect the patients and the public

Zarhin et al. 2018 [29]

Rhetorical and regulatory boundary-work: The case of medical cannabis policy-making in Israel

Israel

Israel

Policy analysis

To examine the MC policymaking process in Israel; the development process was then reviewed to determine the boundaries that dictated between the legal and illegal use of MC