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Table 2 Bivariate and multivariable GLMM analyses of factors associated with injecting drugs alone among 3307 observations from people who inject drugs in Vancouver, Canada, 2016–2018

From: Injecting drugs alone during an overdose crisis in Vancouver, Canada

Variable

Unadjusted

Adjusted

Odds ratio

(95% CI)

p value

Odds ratio

(95% CI)

p value

Age

(per year older)

1.01 (0.99–1.02)

0.234

–

–

Sex

(male vs. female)

2.42 (1.75–3.35)

 < 0.001

1.69 (1.20–2.37)

0.002

Indigenous ancestry

(Self-identified vs. other)

0.55 (0.39–0.76)

 < 0.001

0.71 (0.52–0.98)

0.037

Sexual orientation

(LGBT vs. straight)

0.89 (0.61–1.30)

0.547

–

–

Stable relationship

(yes vs. no)

0.27 (0.20–0.35)

 < 0.001

0.30 (0.23–0.39)

 < 0.001

Employmenta

(yes vs. no)

1.24 (0.92–1.66)

0.152

–

–

Homelessness

(yes vs. no)

1.09 (0.80–1.51)

0.579

–

–

DTES residencea

(yes vs. no)

1.37 (1.02–1.83)

0.034

1.43 (1.08–1.91)

0.014

Recent incarcerationa

(yes vs. no)

1.03 (0.63–1.69)

0.907

–

–

Sex worka

(yes vs. no)

0.72 (0.49–1.06)

0.092

–

–

Violencea

(yes vs. no)

1.38 (0.97–1.95)

0.072

1.43 (1.00–2.03)

0.045

Daily heroin usea

(yes vs. no)

0.99 (0.76–1.29)

0.937

–

–

Daily fentanyl usea

(yes vs. no)

1.45 (0.73–2.90)

0.293

–

–

Daily cocaine usea

(yes vs. no)

0.93 (0.56–1.55)

0.781

–

–

Daily crack cocaine usea

(yes vs. no)

1.19 (0.77–1.83)

0.430

–

–

Daily meth usea

(yes vs. no)

1.13 (0.82–1.56)

0.445

–

–

Binge drug usea

(yes vs. no)

1.35 (1.07–1.70)

0.012

1.36 (1.08–1.72)

0.009

Binge alcohol usea

(yes vs. no)

0.99 (0.71–1.37)

0.946

–

–

Drug dealinga

(yes vs. no)

1.03 (0.76–1.39)

0.845

–

–

Weekly OPS/SCS usea

(yes vs. no)

0.97 (0.73–1.28)

0.811

–

–

Non-fatal overdosea

(yes vs. no)

0.84 (0.62–1.12)

0.236

–

–

Depressionb

(≥ 22 vs. < 22)

1.32 (0.93–1.89)

0.124

–

–

PTSDc

(≥ 31 vs. < 31)

1.28 (0.87–1.89)

0.217

–

–

  1. All drug use variables refer to non-injection and injection use
  2. CI confidence interval, DTES Downtown Eastside
  3. aBehaviours/events in the past 6 months
  4. bMeasured using the Centre for Epidemiologic Studies Depression Scale (CES-D) – >  = 22 at Baseline
  5. cMeasured using the Posttraumatic Stress Disorder Checklist for DSM-5 (PCL-5)-cut-point score of ≥ 31