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Table 2 Recovery of morphine after hot extraction and filtration

From: Effect of filtration on morphine and particle content of injections prepared from slow-release oral morphine tablets

Filtration

Volume of extract

(ml)

Amount of morphine

(mg)

P versus cig.

filter alone*

None

3.0

58.9 ± 1.3

 

Cigarette filter

   

First filtrate

2.1 ± 0.1

42.4 ± 0.9

 

First rinse

1.0 ± 0.1

9.1 ± 1.9

 

Second rinse

1.1 ± 0.1

2.7 ± 0.1

 

Total

4.1 ± 0.1

54.3 ± 2.6

 

Cotton wool

   

First filtrate

1.6 ± 0.2

35.3 ± 4.4

 

First rinse

1.1 ± 0.0

12.1 ± 2.3

 

Second rinse

1.0 ± 0.2

5.2 ± 0.6

 

Total

3.8 ± 0.3

52.6 ± 3.1

0.393

0.45 μm filter

   

First filtrate

1.9 ± 0.2

41.2 ± 2.3

 

Rinse

0.9 ± 0.1

10.7 ± 2.4

 

Total

2.8 ± 0.2

51.8 ± 1.9

0.203

Combined filtration

   

Cig.+ 0.45 μm filter

4.5 ± 0.3

52.4 ± 1.6

0.400

Cig. + 0.22 μm filter

4.3 ± 0.6

49.6 ± 2.0

0.096

  1. Data are mean ± SD, N = 3.
  2. *Comparison of morphine recovery by Mann-Whitney U test (a non-parametric analogue of the t-test), 2-tailed. Results are consistent with parametric analysis with Games-Howell post-hoc tests.
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Harm Reduction Journal

ISSN: 1477-7517