Table 5 Intention to treat analysis examining impact of OST participation on social and behavioral outcomes (with baseline replacement for lost to follow up)
Baseline (T0) | 6 weeks (T1) | 6 months (T2) | 12 months (T3) | P valuea | T0–T1 | T0–T2 | T0–T3 | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
n (%) | n (%) | n (%) | n (%) | Effect sizeb | P valuec | Effect sizeb | P valuec | Effect sizeb | P valuec | ||
Injecting drug use (past 4 weeks) | 73 (98.7) | 7 (9.5) | 19 (25.7) | 20 (27.0) | 0.000 | 2.286 | 0.000 | 1.850 | 0.000 | 1.820 | 0.000 |
Shared needle for injection (past 4 weeks) | 37 (50) | 3 (4.1) | 10 (13.5) | 10 (13.5) | 0.000 | 1.163 | 0.000 | 0.818 | 0.000 | 0.818 | 0.000 |
Property crime (past 4 weeks) | 42 (56.8) | 3 (4.1) | 13 (17.6) | 12 (16.2) | 0.000 | 1.299 | 0.000 | 0.841 | 0.000 | 0.879 | 0.000 |
Anxiety symptoms (GAD-2: ≥ 3)d | 30 (40.5) | 3 (4.05) | 9 (12.2) | 11 (14.9) | 0.000 | 0.975 | 0.000 | 0.667 | 0.000 | 0.588 | 0.000 |
Depression symptoms (PHQ-9: ≥ 10)e | 55 (74.3) | 4 (5.4) | 22 (29.7) | 16 (21.6) | 0.000 | 1.609 | 0.000 | 0.926 | 0.000 | 1.112 | 0.000 |
Current suicidal ideation (PHQ-9: item 9)f | 44 (59.5) | 12 (16.2) | 19 (25.7) | 22 (29.7) | 0.000 | 0.933 | 0.000 | 0.699 | 0.000 | 0.609 | 0.000 |
Poor physical health (self-perceived) | 55 (74.3) | 4 (5.4) | 10 (13.5) | 14 (18.9) | 0.000 | 1.609 | 0.000 | 1.326 | 0.000 | 1.179 | 0.000 |
Poor family relationships | 53 (71.6) | 2 (2.7) | 17 (23) | 16 (21.6) | 0.000 | 1.687 | 0.000 | 1.017 | 0.000 | 1.051 | 0.000 |
Very hopeful for future | 9 (12.2) | 16 (21.6) | 28 (37.8) | 32 (43.2) | 0.000 | 0.253 | 0.127 | 0.611 | 0.000 | 0.721 | 0.000 |
Employment (employed) | 42 (56.8) | 38 (52.8) | 43 (60.6) | 53 (71.6) | 0.007 | 0.080 | 0.439 | 0.077 | 0.832 | 0.310 | 0.016 |
Participation in family events | 50 (67.6) | 51 (68.9) | 57 (77) | 60 (81.1) | 0.079 | 0.028 | 0.847 | 0.211 | 0.189 | 0.312 | 0.018 |