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Fig. 1 | Harm Reduction Journal

Fig. 1

From: Underreporting of non-study cigarette use by study participants confounds the interpretation of results from ambulatory clinical trial of reduced nicotine cigarettes

Fig. 1

Mean and median non-study CPD at week 6. Mean and median non-study CPD at week 6 for groups assigned RNC including participants’ self-report from Donny et al. [3], estimates based on group averages from Zhang et al. [19], estimates from this analysis based on nicotine content of the assigned cigarettes in tobacco filler, smoke nicotine yield under ISO and Canadian Intense smoking conditions, respectively. All estimated mean non-study CPD numbers from this analysis are significantly higher than those self-reported in Donny et al. [3] (p < 0.0001, Wilcoxon matched-pairs signed-rank test). Median self-reported non-study CPD numbers in Donny et al. [3] were zero for all groups

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Harm Reduction Journal

ISSN: 1477-7517